Текст книги "Парадокс энергии. Программа преодоления дефицита энергии, усталости и психологического истощения за 5 шагов"

lxxxvii Noble, Emily E., Ted M. Hsu, and Scott E. Kanoski. “Gut to Brain Dysbiosis: Mechanisms Linking Western Diet Consumption, the Microbiome, and Cognitive Impairment.” Frontiers in Behavioral Neuroscience 11 (2017). https://doi.org/10.3389/fnbeh.2017.00009.

lxxxviii Martinez, Adriana, and Abraham J Al-Ahmad. “Effects of Glyphosate and Aminomethylphosphonic Acid on an…” Comparative Study Toxicol Lett, April 2019. https://www.ncbi.nlm.nih.gov/pubmed/3060574 8.

lxxxix Seneff, Stephanie, and Wendya Morley. “Diminished Brain Resilience Syndrome: A Modern Day Neurological Pathology of Increased Susceptibility to Mild Brain Trauma, Concussion, and Downstream Neurodegeneration.” Surgical Neurology International 5, no. 1 (2014): 97. https://doi.org/10.4 103/2152-7806.134 731.

xc Schinkel, Alfred H. “P-Glycoprotein, a Gatekeeper in the Blood – Brain Barrier.” Advanced Drug Delivery Reviews 36 (1999): 179–94.

xci S. Pluchino, C. Alfaro-Cervello, AK. Nunes CA. Peixoto, A. Fernandes D. Brites, R. Bouchard L. Qin, I. Goshen R. Yirmiya, DF. Santos BP. Carreira, HG. Lee KJ. Seong, et al. “Inhibiting the Microglia Activation Improves the Spatial Memory and Adult Neurogenesis in Rat Hippocampus during 4 8 h of Sleep Deprivation.” Journal of Neuroinflammation. BioMed Central, January 1, 1970. https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974 -017-0998-z.

xcii Liu, Yun-Zi, Yun-Xia Wang, and Chun-Lei Jiang. “Inflammation: The Common Pathway of Stress-Related Diseases.” Frontiers in Human Neuroscience 11 (2017). https://doi.org/10.3389/fnhum.2017.00316

xciii Kessel, Sebastiaan P. Van, and Sahar El Aidy. “Bacterial Metabolites Mirror Altered Gut Microbiota Composition in Patients with Parkinson’s Disease.” Journal of Parkinson’s Disease 9, no. s2 (2019). https://doi.org/10.3233/jpd-191780.

xciv Wu, Xinwei, Xuemei Li, Yi Liu, Nannan Yuan, Chengwen Li, Zhimin Kang, Xinlei Zhang, Yuning Xia, Yimeng Hao, and Yongxing Tan. “Hydrogen Exerts Neuroprotective Effects on OGD/R Damaged Neurons in Rat Hippocampal by Protecting Mitochondrial Function via Regulating Mitophagy Mediated by PINK1/Parkin Signaling Pathway.” Brain Research 1698 (2018): 89–98. https://doi.org/10.1016/j.brainres.2018.06.028.

xcv Bourassa, Megan W., Ishraq Alim, Scott J. Bultman, and Rajiv R. Ratan. “Butyrate, Neuroepigenetics and the Gut Microbiome: Can a High Fiber Diet Improve Brain Health?” Neuroscience Letters 625 (2016): 56–63. https://doi.org/10.1016/j.neulet.2016.02.009.

xcvi Kundu, Parag, Hae Ung Lee, Isabel Garcia-Perez, Emmy Xue Yun Tay, Hyejin Kim, Llanto Elma Faylon, Katherine A. Martin, et al. “Neurogenesis and Prolongevity Signaling in Young Germ-Free Mice Transplanted with the Gut Microbiota of Old Mice.” Science Translational Medicine 11, no. 518 (2019). https://doi.org/10.1126/scitranslmed.aau4 760

xcvii Erny, Daniel, Anna Lena Hrabě De Angelis, Diego Jaitin, Peter Wieghofer, Ori Staszewski, Eyal David, Hadas KerenShaul, et al. “Host Microbiota Constantly Control Maturation and Function of Microglia in the CNS.” Nature Neuroscience 18, no. 7 (2015): 965–77. https://doi.org/10.1038/nn.4 030

xcviii Khan, Naiman A, Lauren B Raine, Eric S Drollette, Mark R Scudder, Arthur F Kramer, and Charles H Hillman. “Dietary Fiber Is Positively Associated with Cognitive Control among Prepubertal Children.” The Journal of Nutrition 14 5, no. 1 (2014): 14 3–4 9. https://doi.org/10.394 5/jn.114.1984 57.

xcix Wu, Xinwei, Xuemei Li, Yi Liu, Nannan Yuan, Chengwen Li, Zhimin Kang, Xinlei Zhang, Yuning Xia, Yimeng Hao, and Yongxing Tan. “Hydrogen Exerts Neuroprotective Effects on OGD/R Damaged Neurons in Rat Hippocampal by Protecting Mitochondrial Function via Regulating Mitophagy Mediated by PINK1/Parkin Signaling Pathway.” Brain Research 1698 (2018): 89–98. https://doi.org/10.1016/j.brainres.2018.06.028.

c Dalile, Boushra, Lukas Van Oudenhove, Bram Vervliet, and Kristin Verbeke. “The Role of Short-Chain Fatty Acids in Microbiota-Gut-Brain Communication.” Nature reviews. Gastroenterology & hepatology, 16(8):4 61-4 78. U.S. National Library of Medicine, August 2019. https://pubmed.ncbi.nlm.nih.gov/31123355.

ci Klinedinst, Brandon S., Colleen Pappas, Scott Le, Shan Yu, Qian Wang, Li Wang, Karin Allenspach-Jorn, Jonathan P. Mochel, and Auriel A. Willette. “Aging-Related Changes in Fluid Intelligence, Muscle and Adipose Mass, and Sex-Specific Immunologic Mediation: A Longitudinal UK Biobank Study.” Brain, Behavior, and Immunity 82 (2019): 396–4 05. https://doi.org/10.1016/j.bbi.2019.09.008.

cii Mielke, M. M., V. V. R. Bandaru, N. J. Haughey, J. Xia, L. P. Fried, S. Yasar, M. Albert, et al. “Serum Ceramides Increase the Risk of Alzheimer Disease: The Women’s Health and Aging Study II.” Neurology 79, no. 7 (2012): 633–4 1. https://doi.org/10.1212/wnl.0b013e318264 e380

ciii Ibid: Liu, Yun-Zi, Yun-Xia Wang, and Chun-Lei Jiang. “Inflammation: The Common Pathway of Stress-Related Diseases.” Frontiers in Human Neuroscience 11 (2017). https://doi.org/10.3389/fnhum.2017.00316.

civ Galland, Leo. “The Gut Microbiome and the Brain.” Journal of Medicinal Food 17, no. 12 (2014): 1261–72. https://doi.org/10.1089/jmf.2014.7000.

cv Guenther, G. G., E. R. Peralta, K. R. Rosales, S. Y. Wong, L. J. Siskind, and A. L. Edinger. “Ceramide Starves Cells to Death by Downregulating Nutrient Transporter Proteins.” Proceedings of the National Academy of Sciences 105, no. 4 5 (2008): 174 02–7. https://doi.org/10.1073/pnas.0802781105.

cvi I Carr, Sheryl Teresa. “Insulin and Ketones: Their Roles in Brain Mitochondrial Function.” BYU ScholarsArchive. Brigham Young University, 2017. https://scholarsarchive.byu.edu/etd/6810.

cvii Xu, Youhua, Hua Zhou, and Quan Zhu. “The Impact of Microbiota-Gut-Brain Axis on Diabetic Cognition Impairment.” Frontiers in Aging Neuroscience 9 (2017). https://doi.org/10.3389/fnagi.2017.00106.

cviii Martínez-Lapiscina, Elena H, Pedro Clavero, Estefania Toledo, Ramon Estruch, Jordi Salas-Salvadó, Beatriz San Julián, Ana Sanchez-Tainta, Emilio Ros, Cinta Valls-Pedret, and Miguel Á Martinez-Gonzalez. “Mediterranean Diet Improves Cognition: the PREDIMED-NAVARRA Randomised Trial.” Journal of Neurology, Neurosurgery & Psychiatry 84, no. 12 (2013): 1318–25. https://doi.org/10.1136/jnnp-2012-304 792.

cix Noble, Emily E., Ted M. Hsu, and Scott E. Kanoski. “Gut to Brain Dysbiosis: Mechanisms Linking Western Diet Consumption, the Microbiome, and Cognitive Impairment.” Frontiers in Behavioral Neuroscience 11 (2017). https://doi.org/10.3389/fnbeh.2017.00009.

cx Cabo, Rafael De, and Mark P. Mattson. “Effects of Intermittent Fasting on Health, Aging, and Disease.” New England Journal of Medicine 381, no. 26 (2019): 254 1–51. https://doi.org/10.1056/nejmra1905136.

cxi Cignarella, Francesca, Claudia Cantoni, Laura Ghezzi, Amber Salter, Yair Dorsett, Lei Chen, Daniel Phillips, et al. “Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota.” Cell Metabolism 27, no. 6 (2018). https://doi.org/10.1016/j.cmet.2018.05.006.

cxii Zarrinpar, Amir, Amandine Chaix, Shibu Yooseph, and Satchidananda Panda. “Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome.” Cell Metabolism 20, no. 6 (2014): 1006–17. https://doi.org/10.1016/j.cmet.2014.11.008

cxiii Chaix, Amandine, Emily N.c. Manoogian, Girish C. Melkani, and Satchidananda Panda. “Time-Restricted Eating to Prevent and Manage Chronic Metabolic Diseases.” Annual Review of Nutrition 39, no. 1 (2019): 291–315. https://doi.org/10.114 6/annurev-nutr-082018-124 320.

cxiv Stekovic, Slaven, Sebastian J. Hofer, Norbert Tripolt, Miguel A. Aon, Philipp Royer, Lukas Pein, Julia T. Stadler, et al. “Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-Obese Humans.” Cell Metabolism 30, no. 3 (2019). https://doi.org/10.1016/j.cmet.2019.07.016.

cxv Mitchell, Sarah J., Michel Bernier, Julie A. Mattison, Miguel A. Aon, Tamzin A. Kaiser, R. Michael Anson, Yuji Ikeno, Rozalyn M. Anderson, Donald K. Ingram, and Rafael De Cabo. “Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories.” Cell Metabolism 29, no. 1 (2019). https://doi.org/10.1016/j.cmet.2018.08.011

cxvi Moro, Tatiana, Grant Tinsley, Antonino Bianco, Giuseppe Marcolin, Quirico Francesco Pacelli, Giuseppe Battaglia, Antonio Palma, Paulo Gentil, Marco Neri, and Antonio Paoli. “Effects of Eight Weeks of Time-Restricted Feeding (16/8) on Basal Metabolism, Maximal Strength, Body Composition, Inflammation, and Cardiovascular Risk Factors in Resistance-Trained Males.” Journal of Translational Medicine 14, no. 1 (2016). https://doi.org/10.1186/s12967-016-104 4–0.

cxvii Chaix, Amandine, Amir Zarrinpar, Phuong Miu, and Satchidananda Panda. “Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges.” Cell Metabolism 20, no. 6 (2014): 991–1005. https://doi.org/10.1016/j.cmet.2014.11.00

cxviii Monique Tello, MD. “Intermittent Fasting: Surprising Update.” Harvard Health Blog, February 10, 2020. https://www.health.harvard.edu/blog/intermittent-fasting-surprising-update-2018062914 156

cxix Brown, Andrew W, Michelle M Bohan Brown, and David B Allison. “Belief beyond the Evidence: Using the Proposed Effect of Breakfast on Obesity to Show 2 Practices That Distort Scientific Evidence.” The American Journal of Clinical Nutrition 98, no. 5 (2013): 1298–1308. https://doi.org/10.394 5/ajcn.113.064 4 10

cxx Matheson, Paul J., Mark A. Wilson, and R.neal Garrison. “Regulation of Intestinal Blood Flow.” Journal of Surgical Research 93, no. 1 (2000): 182–96. https://doi.org/10.1006/jsre.2000.5862.

cxxi Wallis, Gareth A, and Javier T Gonzalez. “Is Exercise Best Served on an Empty Stomach?” The Proceedings of the Nutrition Society. U.S. National Library of Medicine, October 18, 2018. https://pubmed.ncbi.nlm.nih.gov/30334 4 99/.

cxxii Chavan, Rohit, Céline Feillet, Sara S. Fonseca Costa, James E. Delorme, Takashi Okabe, Jürgen A. Ripperger, and Urs Albrecht. “Liver-Derived Ketone Bodies Are Necessary for Food Anticipation.” Nature Communications 7, no. 1 (2016). https://doi.org/10.1038/ncomms10580.

cxxiii https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4 74 2855/

cxxiv Longo, Valter D., and Satchidananda Panda. “Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan.” Cell Metabolism 23, no. 6 (2016): 104 8–59. https://doi.org/10.1016/j.cmet.2016.06.001.

cxxv Mindikoglu, Ayse L., Mustafa M. Abdulsada, Antrix Jain, Jong Min Choi, Prasun K. Jalal, Sridevi Devaraj, Melissa P. Mezzari, Joseph F. Petrosino, Antone R. Opekun, and Sung Yun Jung. “Intermittent Fasting from Dawn to Sunset for 3 °Consecutive Days Is Associated with Anticancer Proteomic Signature and Upregulates Key Regulatory Proteins of Glucose and Lipid Metabolism, Circadian Clock, DNA Repair, Cytoskeleton Remodeling, Immune System and Cognitive Function in Healthy Subjects.” Journal of Proteomics 217 (2020): 10364 5. https://doi.org/10.1016/j.jprot.2020.10364 5

cxxvi Rahbar, Alir, Eisa Safavi, Maryam Rooholamini, Fateme Jaafari, Sadegh Darvishi, and Amin Rahbar. “Effects of Intermittent Fasting during Ramadan on Insulin-like Growth Factor-1, Interleukin 2, and Lipid Profile in Healthy Muslims.” International Journal of Preventive Medicine 10, no. 1 (2019): 7. https://doi.org/10.4 103/ijpvm.ijpvm_252_17

cxxvii Gill, Shubhroz, and Satchidananda Panda. “A Smartphone App Reveals Erratic Diurnal Eating Patterns in Humans That Can Be Modulated for Health Benefits.” Cell Metabolism 22, no. 5 (2015): 789–98. https://doi.org/10.1016/j.cmet.2015.09.005.

cxxviii Wahl, Devin, Sean Coogan, Samantha Solon-Biet, Rafael De Cabo, James Haran, David Raubenheimer, Victoria Cogger, Mark Mattson, Stephen Simpson, and David Le Couteur. “Cognitive and Behavioral Evaluation of Nutritional Interventions in Rodent Models of Brain Aging and Dementia.” Clinical Interventions in Aging Volume 12 (2017): 14 19–28. https://doi.org/10.214 7/cia.s14 524 7.

cxxix Schmitt, Karen, Amandine Grimm, Robert Dallmann, Bjoern Oettinghaus, Lisa Michelle Restelli, Melissa Witzig, Naotada Ishihara, et al. “Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics.” Cell Metabolism 27, no. 3 (2018). https://doi.org/10.1016/j.cmet.2018.01.011

cxxx Newman, John C., and Eric Verdin. “Ketone Bodies as Signaling Metabolites.” Trends in Endocrinology & Metabolism 25, no. 1 (2014): 4 2–52. https://doi.org/10.1016/j.tem.2013.09.002.

cxxxi Cabo, Rafael De, and Mark P. Mattson. “Effects of Intermittent Fasting on Health, Aging, and Disease.” New England Journal of Medicine 381, no. 26 (2019): 254 1–51. https://doi.org/10.1056/nejmra1905136

cxxxii Luna‐Sánchez, Marta, Agustín Hidalgo‐Gutiérrez, Tatjana M Hildebrandt, Julio Chaves‐Serrano, Eliana Barriocanal‐Casado, Ángela Santos‐Fandila, Miguel Romero, et al. “CoQ Deficiency Causes Disruption of Mitochondrial Sulfide Oxidation, a New Pathomechanism Associated with This Syndrome.” EMBO Molecular Medicine 9, no. 1 (2016): 78–95. https://doi.org/10.15252/emmm.20160634 5.

cxxxiii Hine, Christopher, and James R. Mitchell. “Calorie Restriction and Methionine Restriction in Control of Endogenous Hydrogen Sulfide Production by the Transsulfuration Pathway.” Experimental Gerontology 68 (2015): 26–32. https://doi.org/10.1016/j.exger.2014.12.010.

cxxxiv Perridon, Bernard W, Henri G D Leuvenink, Jan-Luuk Hillebrands, Harry van Goor, and Eelke M Bos. “The Role of Hydrogen Sulfide in Aging and Age-Related Pathologies.” Aging. Impact Journals LLC, September 27, 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115888.

cxxxv Li, Shuanshuang, and Guandong Yang. “Hydrogen Sulfide Maintains Mitochondrial DNA Replication via Demethylation of TFAM.” Antioxidants & redox signaling. U.S. National Library of Medicine, May 14, 2015. https://pubmed.ncbi.nlm.nih.gov/25758951.

cxxxvi Zhang, Hongbo, Keir J. Menzies, and Johan Auwerx. “The Role of Mitochondria in Stem Cell Fate and Aging.” Development 14 5, no. 8 (2018). https://doi.org/10.124 2/dev.14 34 20.

cxxxvii Ruiz, Atenodoro R., By, Atenodoro R. Ruiz, and Last full review/revision Oct 2019 | Content last modified Oct 2019. “Carbohydrate Intolerance – Gastrointestinal Disorders.” Merck Manuals Professional Edition. Merck Manuals. Accessed September 13, 2020. https://www.merckmanuals.com/professional/gastrointestinal-disorders/malabsorptionsyndromes/carbohydrate-intolerance?query=carbohydrate+intolerance+lactase.

cxxxviii Greenhill, Claire. “Ketogenic Diet Affects Immune Cells in Mice.” Nature Reviews Endocrinology 16, no. 4 (2020): 196–97. https://doi.org/10.1038/s4 1574 -020-0328-x.

cxxxix Goldberg, Emily L., et al. “Ketogenesis Activates Metabolically Protective Γδ T Cells in Visceral Adipose Tissue.” Nature Metabolism, vol. 2, no. 1, 2020, pp. 50–61., doi:10.1038/s4 2255-019-0160-6.

cxl Edwards, Lindsay M., Andrew J. Murray, Cameron J. Holloway, Emma E. Carter, Graham J. Kemp, Ion Codreanu, Helen Brooker, Damian J. Tyler, Peter A. Robbins, and Kieran Clarke. “Short‐Term Consumption of a High‐Fat Diet Impairs Whole‐Body Efficiency and Cognitive Function in Sedentary Men.” The FASEB Journal 25, no. 3 (2010): 1088–96. https://doi.org/10.1096/fj.10-171983.

cxli Miller, Vincent J., Frederick A. Villamena, and Jeff S. Volek. “Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health.” Journal of Nutrition and Metabolism 2018 (2018): 1–27. https://doi.org/10.1155/2018/515764 5.

cxlii Bak, Ann Mosegaard, Mikkel Holm Vendelbo, Britt Christensen, Rikke Viggers, Bo Martin Bibby, Jørgen Rungby, Jens Otto Lunde Jørgensen, Niels Møller, and Niels Jessen. “Prolonged Fasting-Induced Metabolic Signatures in Human Skeletal Muscle of Lean and Obese Men.” Plos One 13, no. 9 (2018). https://doi.org/10.1371/journal.pone.0200817

cxliii Groennebaek, Thomas, and Kristian Vissing. “Impact of Resistance Training on Skeletal Muscle Mitochondrial Biogenesis, Content, and Function.” Frontiers in Physiology 8 (2017). https://doi.org/10.3389/fphys.2017.00713

cxliv Van Proeyen K;Szlufcik K;Nielens H;Pelgrim K;Deldicque L;Hesselink M;Van Veldhoven PP;Hespel P; “Training in the Fasted State Improves Glucose Tolerance during Fat-Rich Diet.” The Journal of physiology. U.S. National Library of Medicine, November 2010. https://pubmed.ncbi.nlm.nih.gov/2083764 5/.

cxlv Contrepois, Kévin, Si Wu, Kegan J. Moneghetti, Daniel Hornburg, Sara Ahadi, Ming-Shian Tsai, Ahmed A. Metwally, et al. “Molecular Choreography of Acute Exercise.” Cell 181, no. 5 (2020). https://doi.org/10.1016/j.cell.2020.04.04 3.

cxlvi Liu, Yan, Yao Wang, Yueqiong Ni, Cynthia K.y. Cheung, Karen S.l. Lam, Yu Wang, Zhengyuan Xia, et al. “Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention.” Cell Metabolism 31, no. 1 (2020). https://doi.org/10.1016/j.cmet.2019.11.001.

cxlvii Glynn, Erin L, Lucy W Piner, Kim M Huffman, Cris A Slentz, Lorraine Elliot-Penry, Hiba AbouAssi, Phillip J White, et al. “Impact of Combined Resistance and Aerobic Exercise Training on Branched-Chain Amino Acid Turnover, Glycine Metabolism and Insulin Sensitivity in Overweight Humans.” Diabetologia 58, no. 10 (October 2015): 2324 –35. https://doi.org/10.1007/s00125-015-3705-6.

cxlviii Tyagi, V., M. Scordo, R. Yoon, Frank A. Liporace, and L. Greene. “Revisiting the Role of Testosterone: Are We Missing Something?: Semantic Scholar.” undefined, January 1, 1970. https://www.semanticscholar.org/paper/Revisiting-the-roleof-testosterone:-Are-we-missing-Tyagi-Scordo/fc3fcc2587271aa7a3c0b3775bda0134 e194 8221

cxlix Neuman H; Forsythe P; Uzan A; Avni O; Koren O; “Antibiotics in Early Life: Dysbiosis and the Damage Done.” FEMS microbiology reviews. U.S. National Library of Medicine, July 2018. https://pubmed.ncbi.nlm.nih.gov/2994 524 0/.

cl McLaren Howard;,Fouad, Atallah; Minkoff, Howard. “Antibiotic Prophylaxis Trials in Obstetrics: A Call for Pediatric Collaboration.” AJP reports. U.S. National Library of Medicine, April 2020. https://pubmed.ncbi.nlm.nih.gov/32309017/.

clii Kalghatgi S;Spina CS;Costello JC;Liesa M;Morones-Ramirez JR;Slomovic S;Molina A;Shirihai OS;Collins JJ; “Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells.” Science translational medicine. U.S. National Library of Medicine, July 2013. https://pubmed.ncbi.nlm.nih.gov/23825301/.

cliii “Ciprofloxacin Has Dramatic Effects on the Mitochondrial Genome.” ScienceDaily. ScienceDaily, October 1, 2018. https://www.sciencedaily.com/releases/2018/10/18100110194 3.htm.

cliv Stefano, George B., Joshua Samuel, and Richard M. Kream. “Antibiotics May Trigger Mitochondrial Dysfunction Inducing Psychiatric Disorders.” American Journal of Case Reports. International Scientific Information, Inc., January 7, 2017. https://www.amjcaserep.com/abstract/index/idArt/8994 78/act/2.

clv Shan, Jiang, and Li Tong. “Antibiotic Drug Piperacillin Induces Neuron Cell Death through Mitochondrial Dysfunction and Oxidative Damage.” Canadian journal of physiology and pharmacology. U.S. National Library of Medicine, July 31, 2017. https://pubmed.ncbi.nlm.nih.gov/28759731/.

clvi Liu, Zhigang, Xiaoshuang Dai, Hongbo Zhang, Renjie Shi, Yan Hui, Xin Jin, Wentong Zhang, et al. “Gut Microbiota Mediates Intermittent-Fasting Alleviation of Diabetes-Induced Cognitive Impairment.” Nature News. Nature Publishing Group, February 18, 2020. https://www.nature.com/articles/s4 14 67-020-14 676-4.

clvii Manyi-Loh, Christy, Sampson Mamphweli, Edson Meyer, and Anthony Okoh. “Antibiotic Use in Agriculture and Its Consequential Resistance in Environmental Sources: Potential Public Health Implications.” MDPI. Multidisciplinary Digital Publishing Institute, March 30, 2018. https://www.mdpi.com/14 20-304 9/23/4 /795.

clix Samsel, Anthony, and Stephanie Seneff. “Glyphosate, Pathways to Modern Diseases III: Manganese, Neurological Diseases, and Associated Pathologies.” Surgical neurology international. Medknow Publications & Media Pvt Ltd, March 24, 2015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4 392553/.

clx Mesnage, Robin, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink, Caroline Amiel, Jean-Michel Panoff, Fiorella Belpoggi, and Michael N Antoniou. “Shotgun Metagenomics and Metabolomics Reveal Glyphosate Alters the Gut Microbiome of Sprague-Dawley Rats by Inhibiting the Shikimate Pathway.” bioRxiv. Cold Spring Harbor Laboratory, January 1, 2019. https://www.biorxiv.org/content/10.1101/870105v1.

clxi “Global Glyphosate Study by The Ramazzini Institute.” Global Glyphosate Study. Accessed September 13, 2020. https://glyphosatestudy.org/.

clxii AJ;, Martinez A;Al-Ahmad. “Effects of Glyphosate and Aminomethylphosphonic Acid on an Isogeneic Model of the Human Blood-Brain Barrier.” Toxicology letters. U.S. National Library of Medicine. Accessed September 13, 2020. https://pubmed.ncbi.nlm.nih.gov/3060574 8/.

clxiii “Comparative Effects of the Roundup and Glyphosate on…” Accessed September 13, 2020. https://www.researchgate.net/publication/7504 567_Comparative_effects_of_the_Roundup_and_glyphosate_on_mitochondrial_oxidative_phosphorylation.

clxiv CH;, Kuo CH;Yang SN;Kuo PL;Hung. “Immunomodulatory Effects of Environmental Endocrine Disrupting Chemicals.” The Kaohsiung journal of medical sciences. U.S. National Library of Medicine. Accessed September 13, 2020. https://pubmed.ncbi.nlm.nih.gov/22871600/.

clxv Petersen, Kate S. “Sewage Sludge, Mulch, and Slow-Release Fertilizers.” EHN. EHN, August 31, 2020. https://www.ehn.org/plastic-in-farm-soil-and-food-264 7384 684.html?rebelltitem=1.

clxvi CH;, Kuo CH;Y ang SN; Kuo PL; Hung. “Immunomodulatory Effects of Environmental Endocrine Disrupting Chemicals.” The Kaohsiung journal of medical sciences. U.S. National Library of Medicine. Accessed September 13, 2020. https://pubmed.ncbi.nlm.nih.gov/22871600/.

clxvii Sunscreens, EWG’s 2020 Guide to. “EWG’s 2020 Guide to Safer Sunscreens.” EWG. Accessed September 13, 2020. https://www.ewg.org/sunscreen/report/the-trouble-with-sunscreen-chemicals/.

clxviii Bosman, Else S., Arianne Y. Albert, Harvey Lui, Jan P. Dutz, and Bruce A. Vallance. “Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome.” Frontiers. Frontiers, October 7, 2019. https://www.frontiersin.org/articles/10.3389/fmicb.2019.024 10/full.

clxix Oliveira, Karen Jesus, Maria Isabel Chiamolera, Gisele Giannocco, Carmen Cabanelas Pazos-Moura, and Tania Maria Ortiga-Carvalho. “Thyroid Function Disruptors: from Nature to Chemicals.” jme. Bioscientifica Ltd, January 1, 2019. https://jme.bioscientifica.com/view/journals/jme/62/1/JME-18-0081.xml.

clxx Mikulic, Matej. “OTC Drug U.S. Retail Revenue 1965–2019.” Statista, July 22, 2020. https://www.statista.com/statistics/307237/otc-sales-in-theus/.

clxxi Jenna Welu, Justin Metzger, and Michael Vasek. “(PDF) Proton Pump Inhibitor Use and Risk of Dementia in…” Proton Pump Inhibitor Use and Risk of Dementia in the Veteran Population. Federal Practitioner, June 2019. https://www.researchgate.net/publication/334 4 4 6750_Proton_Pump_Inhibitor_Use_and_Risk_of_Dementia_in_the_Veteran_Population.

clxxii Stoker, Megan L., Emma Newport, James C. Hulit, A. Phillip West, and Karl J. Morten. “Impact of Pharmacological Agents on Mitochondrial Function: a Growing Opportunity?” Portland Press. Portland Press, November 7, 2019. https://portlandpress.com/biochemsoctrans/article/4 7/6/1757/221033/Impact-of-pharmacological-agents-on-mitochondrial.

clxxiii Lukić, Iva, Dmitriy Getselter, Oren Ziv, Oded Oron, Eli Reuveni, Omry Koren, and Evan Elliott. “Antidepressants Affect Gut Microbiota and Ruminococcus Flavefaciens Is Able to Abolish Their Effects on Depressive-like Behavior.” Nature News. Nature Publishing Group, April 9, 2019. https://www.nature.com/articles/s4 1398-019-04 66-x.

clxxiv “News from #AAIC19: Surprising Differences Found in How Sleep Medications Increase Dementia Risk for Some, Protect Others.” AAIC. https://www.alz.org/aaic/releases_2019/monSLEEP-jul15.asp.

clxxv Hochuli, Michel, Isabelle Aeberli, Adrienne Weiss, Martin Hersberger, Heinz Troxler, Philipp A. Gerber, Giatgen A. Spinas, and Kaspar Berneis. “Sugar-Sweetened Beverages With Moderate Amounts of Fructose, but Not Sucrose, Induce Fatty Acid Synthesis in Healthy Young Men: A Randomized Crossover Study.” OUP Academic. Oxford University Press, June 1, 2014. https://academic.oup.com/jcem/article/99/6/2164 /2537861.

clxxvi Jaiswal, N., Maurya, C.K., Arha, D. et al. Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress. Apoptosis 20, 930–94 7 (2015). https://doi.org/10.1007/s104 95-015-1128-y

clxxvii Luke Story, Luke Story Podcast, “The Deep Science Of Blue Light Toxicity, and Why LED Trashes Your Health with Dr. Alexander Wunsch” Episode 278. https://www.lukestorey.com/lifestylistpodcast/the-deep-science-of-blue-light-toxicity-whyled-trashes-your-health-with-dr-alexander-wunsch-278

clxxviii Pannala, V. R., Camara, A. K., & Dash, R. K. (2016). Modeling the detailed kinetics of mitochondrial cytochrome coxidase: Catalytic mechanism and nitric oxide inhibition. Journal of applied physiology (Bethesda, Md.: 1985), 121(5), 1196–1207.

clxxix Russell, Cindy L. “5 G Wireless Telecommunications Expansion: Public Health and Environmental Implications.” Environmental Research. U.S. National Library of Medicine, April 11, 2018. https://pubmed.ncbi.nlm.nih.gov/2965564 6/.

clxxx “Planetary Electromagnetic Pollution: It is Time to Assess its Impact.” Bandara, Priyanka et al. The Lancet Planetary Health, Volume 2, Issue 12, e512 – e514, December 2018.

clxxxi Rosenbaum, Michael, Kevin D Hall, Juen Guo, Eric Ravussin, Laurel S Mayer, Marc L Reitman, Steven R Smith, B Timothy Walsh, and Rudolph L Leibel. “Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet.” Obesity (Silver Spring, Md.). U.S. National Library of Medicine, June 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922028/.

clxxxii Walton, Chase M., Samuel M. Jacobsen, Blake W. Dallon, Erin R. Saito, Shantelle L. H. Bennett, Lance E. Davidson, David M. Thomson, Robert D. Hyldahl, and Benjamin T. Bikman. “Ketones Elicit Distinct Alterations in Adipose Mitochondrial Bioenergetics.” MDPI. Multidisciplinary Digital Publishing Institute, August 29, 2020. https://www.mdpi.com/14 22-0067/21/17/6255/htm.

clxxxiii Slavin, Joanne. “Fiber and Prebiotics: Mechanisms and Health Benefits.” MDPI. Multidisciplinary Digital Publishing Institute, April 22, 2013. https://www.mdpi.com/2072-664 3/5/4 /14 17.

clxxxiv Zhang, Chenggang, Wenjing Gong, Zhihui Li, Dawen Gao, and Yan Gao. “Research Progress of Gut Flora in Improving Human Wellness.” Food Science and Human Wellness. Elsevier, March 21, 2019. https://www.sciencedirect.com/science/article/pii/S22134 53019300278.

clxxxv Ma, Linqiang, Honggui Li, Jinbo Hu, Juan Zheng, Jing Zhou, Rachel Botchlett, Destiny Matthews, et al. “Indole Alleviates Diet‐Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6‐Phosphofructo‐2‐Kinase/Fructose‐2,6‐Biphosphatase 3.” AASLD. John Wiley & Sons, Ltd, June 29, 2020. https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.31115.

clxxxvi Wang, Dong D., Dong D. Wang From Department of Nutrition (D.D.W., Estefanía Toledo, Estefanía Toledo From Department of Nutrition (D.D.W., Adela Hruby, Adela Hruby From Department of Nutrition (D.D.W., Bernard A. Rosner, et al. “Plasma Ceramides, Mediterranean Diet, and Incident Cardiovascular Disease in the PREDIMED Trial (Prevención Con Dieta Mediterránea).” Circulation, March 9, 2017. https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.024 261.

clxxxvii Meng, Xiao, Ya Li, Sha Li, Yue Zhou, Ren-You Gan, Dong-Ping Xu, and Hua-Bin Li. “Dietary Sources and Bioactivities of Melatonin.” Nutrients. MDPI, April 7, 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC54 09706/.

clxxxviii Coyle, EF., NS. Knight AJ. Murray, AJ. Murray LM. Edwards, LE. Cochlin CJ. Holloway, CJ. Holloway LM. Edwards, EW. Gertz JA. Wisneski, M. Van Bilsen AJ. Gilde, et al. “Dietary Long-Chain, but Not Medium-Chain, Triglycerides Impair Exercise Performance and Uncouple Cardiac Mitochondria in Rats.” Nutrition & Metabolism. BioMed Central, January 1, 1999. https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/174 3-7075-8-55.

clxxxix Bian, Xiaoming, Liang Chi, Bei Gao, Pengcheng Tu, Hongyu Ru, and Kun Lu. “Gut Microbiome Response to Sucralose and Its Potential Role in Inducing Liver Inflammation in Mice.” Frontiers in physiology. Frontiers Media S.A., July 24, 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522834 /.

cxc Yao, C. K., J. G. Muir, and P. R. Gibson. “Review Article: Insights into Colonic Protein Fermentation, Its Modulation and Potential Health Implications.” Wiley Online Library. John Wiley & Sons, Ltd, November 2, 2015. https://onlinelibrary.wiley.com/doi/pdf/10.1111/apt.134 56.

cxci David, L; Maurice, C; Carmody, R; Gootenberg, et al.; “Diet Rapidly and Reproducibly Alters the Human Gut Microbiome.” Nature. U.S. National Library of Medicine, January 2014. https://pubmed.ncbi.nlm.nih.gov/24 336217/.

cxcii Yao, C. K., J. G. Muir, and P. R. Gibson. “Review Article: Insights into Colonic Protein Fermentation, Its Modulation and Potential Health Implications.” Wiley Online Library. John Wiley & Sons, Ltd, November 2, 2015. https://onlinelibrary.wiley.com/doi/pdf/10.1111/apt.134 56.

cxciii Teigen, Levi M, Zhuo Geng, Michael J Sadowsky, Byron P Vaughn, Matthew J Hamilton, and Alexander Khoruts. “Dietary Factors in Sulfur Metabolism and Pathogenesis of Ulcerative Colitis.” Nutrients. MDPI, April 25, 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521024 /.

cxcvii Park, Seonhye, and Yongsoon Park. “Effects of Dietary Fish Oil and Trans Fat on Rat Aorta Histopathology and Cardiovascular Risk Markers.” Nutrition research and practice. The Korean Nutrition Society and The Korean Society of Community Nutrition, 2009. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788173/.